Based on his experience in RNA biology, Assoc Prof Dr Patomporn’s laboratory is the first research group in Thailand to develop an in-house mRNA vaccine prototype for Covid-19 using a novel circular platform of ribonucleic acid (circular mRNA). His platform led to the success in developing the mRNA vaccine prototype within only two months after he rationally engineered a viral antigen, the SARS-CoV-2 spike. His laboratory has also developed molecular toolbox for Covid-19 research, and provided them to Thai scientific communities free of charge to accelerate the field. In 2021, he and his colleagues founded the first Thailand’s start-up for mRNA therapeutics, Bio-Adventure, aiming at translating his innovation to clinics. His next hurdle is to seek investors and angel funds to set up a local biopharma facility for mRNA medicines in Thailand. He hopes that one day his biomedical research and inventions will transform current medicines toward novel therapeutics. His dream legacy would be to invent novel therapeutics based on mRNA medicines for future pandemics, genetic diseases, regenerative medicine, and cancers. Though his life revolves around his scientific community, he enjoys nothing more than a nice meal with his parents and friends, music, films and running.